Title : Eicosanoids inhibit the G-protein-gated inwardly rectifying potassium channel (Kir3) at the Na+/PIP2 gating site.

Pub. Date : 2001 May 4

PMID : 11278615






2 Functional Relationships(s)
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1 Mutation of a single amino acid in the homomeric Kir3.1 to produce Kir3.1(F137S)(N217D) dramatically increased the channel sensitivity to arachidonic acid and Et-1 treatment. Arachidonic Acid potassium inwardly rectifying channel subfamily J member 3 Homo sapiens
2 Mutation of a single amino acid in the homomeric Kir3.1 to produce Kir3.1(F137S)(N217D) dramatically increased the channel sensitivity to arachidonic acid and Et-1 treatment. Arachidonic Acid potassium inwardly rectifying channel subfamily J member 3 Homo sapiens