Pub. Date : 2001 Jan
PMID : 11205902
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells. | alvocidib | ATP binding cassette subfamily B member 6 (Langereis blood group) | Homo sapiens |
2 | Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells. | alvocidib | ATP binding cassette subfamily G member 2 (Junior blood group) | Homo sapiens |
3 | Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells. | alvocidib | ATP binding cassette subfamily G member 2 (Junior blood group) | Homo sapiens |
4 | Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells. | alvocidib | ATP binding cassette subfamily G member 2 (Junior blood group) | Homo sapiens |
5 | Flavopiridol at a concentration of 10 microM was able to prevent MRP-mediated calcein efflux, whereas Pgp-mediated transport of rhodamine 123 was unaffected at flavopiridol concentrations of up to 100 microM. | alvocidib | ATP binding cassette subfamily C member 3 | Homo sapiens |
6 | These results suggest that ABCG2 plays a role in resistance to flavopiridol. | alvocidib | ATP binding cassette subfamily G member 2 (Junior blood group) | Homo sapiens |