Pub. Date : 2001 Feb
PMID : 11159715
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 2. pK(i) values for displacement of [(3)H]-resiniferatoxin from membranes of rVR1 transfected CHO cells were significantly less for anandamide (5.78) than for its structural analogues N-(4-hydroxyphenyl)-arachidonylamide (AM404; 6.18) and N-(3-methoxy-4-hydroxy)benzyl-arachidonylamide (arvanil; 6.77). | [(3)h]-resiniferatoxin | transient receptor potential cation channel, subfamily V, member 1 | Rattus norvegicus |
| 2 | 2. pK(i) values for displacement of [(3)H]-resiniferatoxin from membranes of rVR1 transfected CHO cells were significantly less for anandamide (5.78) than for its structural analogues N-(4-hydroxyphenyl)-arachidonylamide (AM404; 6.18) and N-(3-methoxy-4-hydroxy)benzyl-arachidonylamide (arvanil; 6.77). | CAV protocol | transient receptor potential cation channel, subfamily V, member 1 | Rattus norvegicus |
| 3 | 2. pK(i) values for displacement of [(3)H]-resiniferatoxin from membranes of rVR1 transfected CHO cells were significantly less for anandamide (5.78) than for its structural analogues N-(4-hydroxyphenyl)-arachidonylamide (AM404; 6.18) and N-(3-methoxy-4-hydroxy)benzyl-arachidonylamide (arvanil; 6.77). | anandamide | transient receptor potential cation channel, subfamily V, member 1 | Rattus norvegicus |
| 4 | 3. pEC(50) values for stimulating (45)Ca(2+) uptake into rVR1 transfected CHO cells were significantly less for anandamide (5.80) than for AM404 (6.32) or arvanil (9.29). | CAV protocol | transient receptor potential cation channel, subfamily V, member 1 | Rattus norvegicus |
| 5 | 3. pEC(50) values for stimulating (45)Ca(2+) uptake into rVR1 transfected CHO cells were significantly less for anandamide (5.80) than for AM404 (6.32) or arvanil (9.29). | anandamide | transient receptor potential cation channel, subfamily V, member 1 | Rattus norvegicus |
| 6 | 3. pEC(50) values for stimulating (45)Ca(2+) uptake into rVR1 transfected CHO cells were significantly less for anandamide (5.80) than for AM404 (6.32) or arvanil (9.29). | N-(4-hydroxyphenyl)arachidonylamide | transient receptor potential cation channel, subfamily V, member 1 | Rattus norvegicus |
| 7 | 3. pEC(50) values for stimulating (45)Ca(2+) uptake into rVR1 transfected CHO cells were significantly less for anandamide (5.80) than for AM404 (6.32) or arvanil (9.29). | arvanil | transient receptor potential cation channel, subfamily V, member 1 | Rattus norvegicus |
| 8 | In conclusion, anandamide and certain of its analogues have affinity and efficacy at the rat VR1 receptor. | anandamide | transient receptor potential cation channel, subfamily V, member 1 | Rattus norvegicus |