Title : Distribution of acid sphingomyelinase in human various body fluids.

Pub. Date : 2000 Sep

PMID : 11128869






7 Functional Relationships(s)
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1 Enzyme activities of acid sphingomyelinase (ASM) were determined in various human cell-free body fluids, serum, cerebrospinal fluid, urine, salivary fluid, tear fluid, and synovial fluid, using assay buffers with or without Zn2+ -cation. Zinc sphingomyelin phosphodiesterase 1 Homo sapiens
2 Enzyme activities of acid sphingomyelinase (ASM) were determined in various human cell-free body fluids, serum, cerebrospinal fluid, urine, salivary fluid, tear fluid, and synovial fluid, using assay buffers with or without Zn2+ -cation. Zinc sphingomyelin phosphodiesterase 1 Homo sapiens
3 All ASMs detected in the fluids were stimulated by the addition of Zn2+ -cation, suggesting that those enzymes are secretory ASM derived from ASM gene. Zinc sphingomyelin phosphodiesterase 1 Homo sapiens
4 All ASMs detected in the fluids were stimulated by the addition of Zn2+ -cation, suggesting that those enzymes are secretory ASM derived from ASM gene. Zinc sphingomyelin phosphodiesterase 1 Homo sapiens
5 Because sphingolipids, especially sphingomyelin, are major constituents of a normal diet, especially, milk, eggs, and meat products, we suggest that ASM in the salivary gland may play an important role in the digestion of sphingomyelin in a normal diet. Sphingolipids sphingomyelin phosphodiesterase 1 Homo sapiens
6 Because sphingolipids, especially sphingomyelin, are major constituents of a normal diet, especially, milk, eggs, and meat products, we suggest that ASM in the salivary gland may play an important role in the digestion of sphingomyelin in a normal diet. Sphingomyelins sphingomyelin phosphodiesterase 1 Homo sapiens
7 Because sphingolipids, especially sphingomyelin, are major constituents of a normal diet, especially, milk, eggs, and meat products, we suggest that ASM in the salivary gland may play an important role in the digestion of sphingomyelin in a normal diet. Sphingomyelins sphingomyelin phosphodiesterase 1 Homo sapiens