Title : HIV protease inhibitors block adipogenesis and increase lipolysis in vitro.

Pub. Date : 2000 Aug

PMID : 10996400






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In these cells the PIs, nelfinavir, saquinavir, and ritonavir, reduced triglyceride accumulation, lipogenesis, and expression of the adipose markers, aP2 and LPL. Nelfinavir transcription factor AP-2, alpha Mus musculus
2 In these cells the PIs, nelfinavir, saquinavir, and ritonavir, reduced triglyceride accumulation, lipogenesis, and expression of the adipose markers, aP2 and LPL. Nelfinavir lipoprotein lipase Mus musculus