Title : Contrasting patterns and cellular specificity of transcriptional regulation of the nuclear receptor nerve growth factor-inducible B by haloperidol and clozapine in the rat forebrain.

Pub. Date : 2000 Oct

PMID : 10987852






7 Functional Relationships(s)
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1 Contrasting patterns and cellular specificity of transcriptional regulation of the nuclear receptor nerve growth factor-inducible B by haloperidol and clozapine in the rat forebrain. Haloperidol nuclear receptor subfamily 4, group A, member 1 Rattus norvegicus
2 Contrasting patterns and cellular specificity of transcriptional regulation of the nuclear receptor nerve growth factor-inducible B by haloperidol and clozapine in the rat forebrain. Clozapine nuclear receptor subfamily 4, group A, member 1 Rattus norvegicus
3 An acute treatment with clozapine or haloperidol induces high NGFI-B mRNA levels in the prefrontal and cingulate cortices and in the nucleus accumbens shell. Clozapine nuclear receptor subfamily 4, group A, member 1 Rattus norvegicus
4 An acute treatment with clozapine or haloperidol induces high NGFI-B mRNA levels in the prefrontal and cingulate cortices and in the nucleus accumbens shell. Haloperidol nuclear receptor subfamily 4, group A, member 1 Rattus norvegicus
5 However, haloperidol, but not clozapine, dramatically increases NGFI-B expression in the dorsolateral striatum. Haloperidol nuclear receptor subfamily 4, group A, member 1 Rattus norvegicus
6 In contrast, chronic treatment with clozapine reduces NGFI-B expression below basal levels in the rat forebrain, whereas haloperidol still induces high NGFI-B mRNA levels in the dorsolateral striatum. Clozapine nuclear receptor subfamily 4, group A, member 1 Rattus norvegicus
7 In contrast, chronic treatment with clozapine reduces NGFI-B expression below basal levels in the rat forebrain, whereas haloperidol still induces high NGFI-B mRNA levels in the dorsolateral striatum. Haloperidol nuclear receptor subfamily 4, group A, member 1 Rattus norvegicus