Title : A new aspartyl protease on 21q22.3, BACE2, is highly similar to Alzheimer's amyloid precursor protein beta-secretase.

Pub. Date : 2000

PMID : 10965118






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The BACE2 gene product is a 518 amino acid protein with the signature of an aspartic protease, a 20-residue signal peptide, and two putative N-glycosylation sites. Nitrogen beta-secretase 2 Homo sapiens
2 In addition, and similarly to BACE, BACE2 differs from the other members of the human aspartic protease family in the number and distribution of putative disulfide bonds and in the presence of an extended C-terminal region which contains a predicted transmembrane segment. Disulfides beta-secretase 2 Homo sapiens