Title : Variability in activity of hepatic CYP3A4 in patients infected with HIV.

Pub. Date : 2000 Aug

PMID : 10939550






1 Functional Relationships(s)
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1 STUDY OBJECTIVES: To evaluate hepatic cytochrome P450 (CYP) 3A4 activity in patients infected with the human immunodeficiency virus (HIV) using the erythromycin breath test (ERMBT), and to examine the relationship of the ERMBT to plasma concentrations of indinavir and nelfinavir. Nelfinavir cytochrome P450 family 3 subfamily A member 4 Homo sapiens