Title : Divergent effects of platelet-endothelial cell adhesion molecule-1 and beta 3 integrin blockade on leukocyte transmigration in vivo.

Pub. Date : 2000 Jul 1

PMID : 10861081






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The anti-PECAM-1 mAb suppressed leukocyte extravasation, but not leukocyte rolling or firm adhesion, elicited by IL-1beta in a dose-dependent manner (e.g., 67% inhibition at 10 mg/kg 37 Fab), but had no effect on FMLP-induced leukocyte responses. FAB protocol platelet and endothelial cell adhesion molecule 1 Rattus norvegicus