Title : Activation of deltaF508 CFTR in a cystic fibrosis respiratory epithelial cell line by 4-phenylbutyrate, genistein and CPX.

Pub. Date : 2000 May

PMID : 10853862






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Activation of deltaF508 CFTR in a cystic fibrosis respiratory epithelial cell line by 4-phenylbutyrate, genistein and CPX. 4-phenylbutyric acid CF transmembrane conductance regulator Homo sapiens
2 The increased efflux of chloride after 4-phenylbutyrate treatment can be explained by the fact that 4-phenylbutyrate allows the deltaF508 cystic fibrosis transmembrane conductance regulator to escape degradation and to be transported to the cell surface. 4-phenylbutyric acid CF transmembrane conductance regulator Homo sapiens
3 The increased efflux of chloride after 4-phenylbutyrate treatment can be explained by the fact that 4-phenylbutyrate allows the deltaF508 cystic fibrosis transmembrane conductance regulator to escape degradation and to be transported to the cell surface. 4-phenylbutyric acid CF transmembrane conductance regulator Homo sapiens