PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10853862-0 2000 Activation of deltaF508 CFTR in a cystic fibrosis respiratory epithelial cell line by 4-phenylbutyrate, genistein and CPX. 4-phenylbutyric acid 86-102 CF transmembrane conductance regulator Homo sapiens 24-28 10853862-8 2000 The increased efflux of chloride after 4-phenylbutyrate treatment can be explained by the fact that 4-phenylbutyrate allows the deltaF508 cystic fibrosis transmembrane conductance regulator to escape degradation and to be transported to the cell surface. 4-phenylbutyric acid 39-55 CF transmembrane conductance regulator Homo sapiens 138-189 10853862-8 2000 The increased efflux of chloride after 4-phenylbutyrate treatment can be explained by the fact that 4-phenylbutyrate allows the deltaF508 cystic fibrosis transmembrane conductance regulator to escape degradation and to be transported to the cell surface. 4-phenylbutyric acid 100-116 CF transmembrane conductance regulator Homo sapiens 138-189 8003768-1 1994 The purpose of this study was to investigate whether an intraperitoneal injection of interleukin-1 beta (IL-1 beta) affects noradrenaline release in the spleen through its action on the brain of conscious rats. Norepinephrine 124-137 interleukin 1 beta Rattus norvegicus 105-114 8003768-5 1994 The intraperitoneal injection of IL-1 beta (100 ng/kg) produced an immediate and significant increase in the noradrenaline levels in the spleen. Norepinephrine 109-122 interleukin 1 beta Rattus norvegicus 33-42 8003768-7 1994 An intracerebroventricular (ICV) injection of a corticotropin-releasing factor (CRF) antagonist (alpha-helical CRF9-41, 30 micrograms) significantly attenuated the IL-1 beta-induced increase in the noradrenaline release. Norepinephrine 198-211 interleukin 1 beta Rattus norvegicus 164-173 8003768-9 1994 These results suggest that the intraperitoneal injection of IL-1 beta facilitates noradrenaline release in the spleen through activation of the sympathetic nerve, and the increased sympathetic activity is, at least in part, due to the excitation of neurons containing CRF in the brain. Norepinephrine 82-95 interleukin 1 beta Rattus norvegicus 60-69 8384045-0 1993 Central administration of interleukin-1 beta increases norepinephrine turnover in the spleen. Norepinephrine 55-69 interleukin 1 beta Rattus norvegicus 26-44 8376550-0 1993 Norepinephrine and vasoactive intestinal peptide induce IL-6 secretion by astrocytes: synergism with IL-1 beta and TNF alpha. Norepinephrine 0-14 interleukin 1 beta Rattus norvegicus 101-110 8384045-3 1993 In this study, we have determined whether ICV administration of IL-1 beta has an effect on sympathetic outflow and norepinephrine (NE) turnover in the spleen. Norepinephrine 115-129 interleukin 1 beta Rattus norvegicus 64-73 8393485-0 1993 Interleukin-1 beta augments release of norepinephrine, dopamine, and serotonin in the rat anterior hypothalamus. Norepinephrine 39-53 interleukin 1 beta Rattus norvegicus 0-18 8393485-3 1993 IL-1 beta (1 ng) injected directly into the AHY elicited release of norepinephrine (NE), dopamine (DA), and 5-HT, as well as increases in their metabolites, 4-hydroxy-3-methoxyphenylglycol, 3,4-dihydroxyphenylacetic acid, 4-hydroxy-3-methoxyphenylacetic acid, and 5-hydroxyindole-3-acetic acid, in the AHY. Norepinephrine 68-82 interleukin 1 beta Rattus norvegicus 0-9 8430802-0 1993 Interleukin-1 beta modulation of norepinephrine release from rat myenteric nerves. Norepinephrine 33-47 interleukin 1 beta Rattus norvegicus 0-18 2171909-15 1990 Thus, the secretion of ACTH stimulated by the action of IL-1 beta at the ME depends, in part, on the local secretion of norepinephrine and epinephrine interacting with both alpha and beta adrenergic receptors. Norepinephrine 120-134 interleukin 1 beta Rattus norvegicus 56-65 8505861-1 1993 The purpose of this study was to investigate the effects of circulating interleukin-1 beta (IL-1 beta) on the release of norepinephrine (NE) in the paraventricular nucleus (PVN). Norepinephrine 121-135 interleukin 1 beta Rattus norvegicus 72-90 8505861-1 1993 The purpose of this study was to investigate the effects of circulating interleukin-1 beta (IL-1 beta) on the release of norepinephrine (NE) in the paraventricular nucleus (PVN). Norepinephrine 121-135 interleukin 1 beta Rattus norvegicus 92-101 2573510-3 1989 The iv or intracerebroventricular injection of either Il-1 alpha or Il-1 beta caused dose-related increases in plasma ACTH, epinephrine, and norepinephrine levels. Norepinephrine 141-155 interleukin 1 beta Rattus norvegicus 68-77