Pub. Date : 2000 Jul 28
PMID : 10801821
6 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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| 1 | In TAFI activation, however, alanine mutations cause a 50% reduction at Tyr-337, 67% reductions at Asp-338 and Leu-339, and 90% or greater reductions at Val-340, Asp-341, and Glu-343. | Alanine | carboxypeptidase B2 | Homo sapiens | ||
| 2 | In TAFI activation, however, alanine mutations cause a 50% reduction at Tyr-337, 67% reductions at Asp-338 and Leu-339, and 90% or greater reductions at Val-340, Asp-341, and Glu-343. | Aspartic Acid | carboxypeptidase B2 | Homo sapiens | ||
| 3 | In TAFI activation, however, alanine mutations cause a 50% reduction at Tyr-337, 67% reductions at Asp-338 and Leu-339, and 90% or greater reductions at Val-340, Asp-341, and Glu-343. | Glutamic Acid | carboxypeptidase B2 | Homo sapiens | ||
| 4 | A mutation at Asp-349 in the peptide connecting EGF3 to EGF4 eliminated activity against both TAFI and protein C. Oxidation of Met-388 in the peptide connecting EGF5 to EGF6 reduced the rate of protein C activation by 80% but marginally, if at all, affected the rate of TAFI activation. | Aspartic Acid | carboxypeptidase B2 | Homo sapiens | ||
| 5 | A mutation at Asp-349 in the peptide connecting EGF3 to EGF4 eliminated activity against both TAFI and protein C. Oxidation of Met-388 in the peptide connecting EGF5 to EGF6 reduced the rate of protein C activation by 80% but marginally, if at all, affected the rate of TAFI activation. | Aspartic Acid | carboxypeptidase B2 | Homo sapiens | ||
| 6 | Mutation at Phe-376 severely reduced protein C activation but only marginally influenced that of TAFI. | Phenylalanine | carboxypeptidase B2 | Homo sapiens | ||