Title : Mitochondrial DNA damage and a hypoxic response are induced by CoCl(2) in rat neuronal PC12 cells.

Pub. Date : 2000 May 15

PMID : 10773083






1 Functional Relationships(s)
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1 In addition, the levels of proteins involved in cellular responses to hypoxia, ROS and nuclear DNA damage; hypoxia-inducible factor 1alpha(HIF-1alpha), p53, p21 and PCNA were also modulated temporally. Reactive Oxygen Species hypoxia inducible factor 1 subunit alpha Rattus norvegicus