Title : Induction of apoptosis by the O-hydroxyethyl-D(Ser)(8)-cyclosporine A derivative SDZ IMM 125 in rat hepatocytes.

Pub. Date : 2000 Apr

PMID : 10734149






3 Functional Relationships(s)
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1 The specific caspase-3 inhibitor, Ac-Asp-Glu-Val-Asp-aldehyde, inhibited caspase-3 activation and attenuated SDZ IMM 125-induced apoptosis and lactate dehydrogenase leakage. acetyl-aspartyl-glutamyl-valyl-aspartal caspase 3 Rattus norvegicus
2 The specific caspase-3 inhibitor, Ac-Asp-Glu-Val-Asp-aldehyde, inhibited caspase-3 activation and attenuated SDZ IMM 125-induced apoptosis and lactate dehydrogenase leakage. acetyl-aspartyl-glutamyl-valyl-aspartal caspase 3 Rattus norvegicus
3 The specific caspase-3 inhibitor, Ac-Asp-Glu-Val-Asp-aldehyde, inhibited caspase-3 activation and attenuated SDZ IMM 125-induced apoptosis and lactate dehydrogenase leakage. SDZ IMM 125 caspase 3 Rattus norvegicus