Pub. Date : 1999 Dec 16
PMID : 10716232
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The nicotinic acetylcholine receptor agonist ABT-594 increases FGF-2 expression in various rat brain regions. | 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid | cholinergic receptor nicotinic alpha 2 subunit | Rattus norvegicus |
| 2 | The nicotinic acetylcholine receptor agonist ABT-594 increases FGF-2 expression in various rat brain regions. | 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid | fibroblast growth factor 2 | Rattus norvegicus |
| 3 | The present experiments were designed to extend previous work showing that acute intermittent (-)nicotine treatment upregulates the level of fibroblast growth factor-2 (FGF2) mRNA in several rat brain regions, by the use of the nicotinic acetylcholine receptor (nAChR) agonist ABT-594 with preferential selectivity for the alpha4beta2 nAChR subtype. | 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid | fibroblast growth factor 2 | Rattus norvegicus |
| 4 | The present experiments were designed to extend previous work showing that acute intermittent (-)nicotine treatment upregulates the level of fibroblast growth factor-2 (FGF2) mRNA in several rat brain regions, by the use of the nicotinic acetylcholine receptor (nAChR) agonist ABT-594 with preferential selectivity for the alpha4beta2 nAChR subtype. | 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid | fibroblast growth factor 2 | Rattus norvegicus |
| 5 | The effects of ABT-594 on FGF-2 expression were antagonized by the preferential alpha4beta2 antagonist dihydrobetaerythroidine (DHbetaE), but not by alpha7 antagonist methyllycaconitine (MLA). | 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid | fibroblast growth factor 2 | Rattus norvegicus |