Protein Name | fibroblast growth factor 2 |
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Organism | Rattus norvegicus |
Gene ID | 54250 |
Gene Symbol | Fgf2 |
UniProt | P13109 (FGF2_RAT) |
Relationships |
Total Number of functionally related compound(s) :
785
Total Number of Articles : 1165 |
Description |
fibroblast growth factor 2 |
Gene Summary |
Enables fibroblast growth factor receptor binding activity. Involved in several processes, including angiogenesis involved in coronary vascular morphogenesis; paracrine signaling; and positive regulation of cell population proliferation. Acts upstream of or within fibroblast growth factor receptor signaling pathway. Located in cytoplasm; extracellular space; and nucleus. Used to study pulmonary hypertension. Biomarker of bladder disease; decubitus ulcer; diabetic retinopathy; hypertension; and retinal vein occlusion. Human ortholog(s) of this gene implicated in several diseases, including Parkinsonism; corneal neovascularization; diabetic neuropathy; gastric ulcer; and impotence. Orthologous to human FGF2 (fibroblast growth factor 2). [provided by Alliance of Genome Resources, Apr 2022] |
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