Title : A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling.

Pub. Date : 2000 Feb

PMID : 10648629






1 Functional Relationships(s)
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1 Finally, expression of the gene for the lipid phosphatase PTEN, which dephosphorylates PtdIns(3,4, 5)P3, inhibits EGF signaling and translocation of Gab1 to the plasma membrane. phosphatidylinositol 3,4,5-triphosphate phosphatase and tensin homolog Homo sapiens