Title : The gp49A gene has extensive sequence conservation with the gp49B gene and provides gp49A protein, a unique member of a large family of activating and inhibitory receptors of the immunoglobulin superfamily.

Pub. Date : 1999 Dec

PMID : 10630292






1 Functional Relationships(s)
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1 We now report the cloning, complete sequence, and organization of the mouse gp49A gene that encodes the only member of this newly-appreciated family without either of two mutually exclusive functional motifs, namely, immunoreceptor tyrosine-based inhibitory motifs (ITIMs) or a charged transmembrane amino acid for heterodimerization with activation molecules. Tyrosine leukocyte immunoglobulin-like receptor, subfamily B, member 4B Mus musculus