Title : Mechanisms of photoreceptor cell apoptosis induced by N-methyl-N-nitrosourea in Sprague-Dawley rats.

Pub. Date : 1999 Nov

PMID : 10576206






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Therefore MNU-induced photoreceptor cell death was attributed to DNA adduct formation restricted to photoreceptor cell nuclei leading to photoreceptor cell apoptosis by up-regulation of Bax protein, down-modulation of Bcl-2 protein, and activation of caspases 3, 6, and 8. Methylnitrosourea caspase 3 Rattus norvegicus