Title : Hepatic metabolism of diclofenac: role of human CYP in the minor oxidative pathways.

Pub. Date : 1999 Sep 1

PMID : 10449188






1 Functional Relationships(s)
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1 Comparison of data obtained with CYP-expressing cells and human hepatocytes suggests that CYP2C8 > CYP2C19 approximately CYP2C18 >> CYP2B6 are the isoforms implicated in the 5-hydroxylation of diclofenac in vivo. Diclofenac cytochrome P450 family 2 subfamily C member 18 Homo sapiens