Title : Role of PTP-1B in aortic smooth muscle cell motility and tyrosine phosphorylation of focal adhesion proteins.

Pub. Date : 1999 Jul

PMID : 10409197






2 Functional Relationships(s)
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1 Our findings indicate that PTP-1B is a negative regulator of RASMC motility via modulation of phosphotyrosine levels in several focal adhesion proteins and suggest the involvement of PTP-1B in events such as atherosclerosis and restenosis, which are associated with increased vascular smooth muscle cell motility. rasmc protein tyrosine phosphatase, non-receptor type 1 Rattus norvegicus
2 Our findings indicate that PTP-1B is a negative regulator of RASMC motility via modulation of phosphotyrosine levels in several focal adhesion proteins and suggest the involvement of PTP-1B in events such as atherosclerosis and restenosis, which are associated with increased vascular smooth muscle cell motility. Phosphotyrosine protein tyrosine phosphatase, non-receptor type 1 Rattus norvegicus