Pub. Date : 1999 May
PMID : 10374244
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibitory effect of resveratrol on interleukin 6 release by stimulated peritoneal macrophages of mice. | Resveratrol | interleukin 6 | Mus musculus |
| 2 | The effects of resveratrol on Il-6 release by mouse peritoneal macrophages stimulated with calcium ionophore A23187 and fMLP were explored. | Resveratrol | interleukin 6 | Mus musculus |
| 3 | Resveratrol, at a concentration range from 5 x 10(-6) to 4 x 10(-5) mol.l-1, was found to dose-dependently inhibit IL-6 release by cultured macrophages induced by A23187 and fMLP, and showed no direct cytotoxic effect, but induced proliferation of cultured mouse thymus cells. | Resveratrol | interleukin 6 | Mus musculus |
| 4 | These results suggest that the blocking of calcium ion influx into cells by reveratrol is one of the possible mechanisms of the IL-6 biosynthesis inhibitory action of resveratrol. | Resveratrol | interleukin 6 | Mus musculus |