Title : Apoptosis and growth inhibition in malignant lymphocytes after treatment with arsenic trioxide at clinically achievable concentrations.

Pub. Date : 1999 May 5

PMID : 10328107






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 As2O3 induced PML (promyelocytic leukemia) protein degradation but did not modulate expression of cell cycle-related proteins, including c-myc, retinoblastoma protein, cyclin-dependent kinase 4, cyclin D1, and p53, or expression of differentiation-related antigens. Arsenic Trioxide PML nuclear body scaffold Homo sapiens
2 As2O3 induced PML (promyelocytic leukemia) protein degradation but did not modulate expression of cell cycle-related proteins, including c-myc, retinoblastoma protein, cyclin-dependent kinase 4, cyclin D1, and p53, or expression of differentiation-related antigens. Arsenic Trioxide PML nuclear body scaffold Homo sapiens