Title : Resveratrol, a natural product derived from grape, exhibits antiestrogenic activity and inhibits the growth of human breast cancer cells.

Pub. Date : 1999 Jun

PMID : 10228948






2 Functional Relationships(s)
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1 Resveratrol in a dose-dependent fashion antagonized the stimulation by E2 of progesterone receptor gene expression in MCF-7 cells. Resveratrol progesterone receptor Homo sapiens
2 Moreover, expression of transforming growth factor-alpha and insulin-like growth factor I receptor mRNA was inhibited while the expression of transforming growth factor beta2 mRNA was significantly elevated in MCF-7 cells cultivated in the presence of resveratrol (10(-5) M). Resveratrol transforming growth factor beta 2 Homo sapiens