Title : C-peptide induces a concentration-dependent dilation of skeletal muscle arterioles only in presence of insulin.

Pub. Date : 1999 Apr

PMID : 10199846






2 Functional Relationships(s)
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1 The arteriolar dilation to C-peptide in the presence of insulin was completely inhibited by administration of NG-nitro-L-arginine (10(-4) M). Nitroarginine insulin 2 Rattus norvegicus
2 These results indicate that C-peptide has the capacity to evoke arteriolar dilation in skeletal muscle via a nitric oxide-mediated mechanism that appears to be enhanced by an interaction with insulin. Nitric Oxide insulin 2 Rattus norvegicus