Pub. Date : 1999 Mar
PMID : 10103099
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cytochrome c release and caspase-3 activation during colchicine-induced apoptosis of cerebellar granule cells. | Colchicine | caspase 3 | Rattus norvegicus |
| 2 | In this study we investigated the involvement of cytochrome c release and caspase-3 activation during colchicine-induced CGC apoptosis. | Colchicine | caspase 3 | Rattus norvegicus |
| 3 | An involvement of group II caspases (which includes caspase-3) was demonstrated by the proteolytic degradation of poly(ADP-ribose) polymerase (PARP) after 18 h exposure to colchicine. | Colchicine | caspase 3 | Rattus norvegicus |
| 4 | Activation of caspase-3 during colchicine-induced apoptosis may be mediated by cytochrome c since there was a close correlation between the time courses of cytochrome c release from the mitochondria and of caspase-3 activation. | Colchicine | caspase 3 | Rattus norvegicus |
| 5 | Activation of caspase-3 during colchicine-induced apoptosis may be mediated by cytochrome c since there was a close correlation between the time courses of cytochrome c release from the mitochondria and of caspase-3 activation. | Colchicine | caspase 3 | Rattus norvegicus |