Title : Neuroendocrine dysplasia in mice lacking protein tyrosine phosphatase sigma.

Pub. Date : 1999 Mar

PMID : 10080191






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 On the basis of its expression and homology with the Drosophila melanogasterorthologues DPTP99 and DPTP100A (refs 5,6), which have roles in the targeting of axonal growth cones, we hypothesized that PTP-sigma may also have a modulating function in cell-cell interactions, as well as in axon guidance during mammalian embryogenesis. dptp99 protein tyrosine phosphatase, receptor type, S Mus musculus
2 On the basis of its expression and homology with the Drosophila melanogasterorthologues DPTP99 and DPTP100A (refs 5,6), which have roles in the targeting of axonal growth cones, we hypothesized that PTP-sigma may also have a modulating function in cell-cell interactions, as well as in axon guidance during mammalian embryogenesis. dptp100a protein tyrosine phosphatase, receptor type, S Mus musculus
3 These results suggest that tyrosine phosphorylation-dependent signalling pathways regulated by PTP-sigma influence the proliferation and/or adhesiveness of various cell types in the developing hypothalamo-pituitary axis. Tyrosine protein tyrosine phosphatase, receptor type, S Mus musculus