Protein Name protein tyrosine phosphatase receptor type S
Organism Mus musculus
Gene ID 19280
Gene Symbol

Ptprs

UniProt B0V2N1 (PTPRS_MOUSE), Q3TQ52 (Q3TQ52_MOUSE)
Relationships Total Number of functionally related compound(s) : 31
Total Number of Articles : 27
Description

protein tyrosine phosphatase receptor type S

Gene Summary

Enables chondroitin sulfate binding activity; heparin binding activity; and protein tyrosine phosphatase activity. Involved in several processes, including negative regulation of neuron projection development; peptidyl-tyrosine dephosphorylation; and regulation of postsynaptic density assembly. Acts upstream of or within central nervous system development and establishment of endothelial intestinal barrier. Located in plasma membrane. Is active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and presynaptic membrane. Is expressed in several structures, including adipose tissue; genitourinary system; gut; nervous system; and sensory organ. Orthologous to human PTPRS (protein tyrosine phosphatase receptor type S). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • receptor-type tyrosine-protein phosphatase S
  • Receptor-type tyrosine-protein phosphatase sigma
  • tissue-specific protein tyrosine phosphatase
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Properties