Pub. Date : 1999 Jan 11
PMID : 10048758
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In this study, experiments with CEM x 174 cells, a hybrid of human T and B cells, were performed to investigate the effects of the tumor promoter heptachlor and its congeners chlordane and toxaphene on retinoblastoma (Rb) gene expression. | Heptachlor | RB transcriptional corepressor 1 | Homo sapiens |
2 | In this study, experiments with CEM x 174 cells, a hybrid of human T and B cells, were performed to investigate the effects of the tumor promoter heptachlor and its congeners chlordane and toxaphene on retinoblastoma (Rb) gene expression. | Heptachlor | RB transcriptional corepressor 1 | Homo sapiens |
3 | The results indicated that heptachlor, chlordane or toxaphene, in the range of 10-50 microM, were able to reduce Rb protein levels in a concentration-dependent manner. | Heptachlor | RB transcriptional corepressor 1 | Homo sapiens |