Pub. Date : 1999 Feb 15
PMID : 9933021
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Molecular O2 is an obligatory substrate for the successive syntheses of 17alpha-OH pregnenolone and dehydroepiandrosterone (DHEA) by cytochrome P450c17 in the zona reticularis of the adrenal cortex, in which it is suggested that arteriosclerosis --> decreased blood flow --> O2 and glucose deficit --> decreased O2-requiring synthesis of DHEA --> eventual decrease in number of DHEA-synthesizing cells. | Glucose | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |