Pub. Date : 1999 Jan 29
PMID : 9931427
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Identification of CYP3A4 as the major enzyme responsible for 25-hydroxylation of 5beta-cholestane-3alpha,7alpha,12alpha-triol in human liver microsomes. | 5beta-cholestane-3alpha | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 2 | A strong correlation was observed between formation of 25-hydroxylated 5beta-cholestane-3alpha,7alpha,12alpha-triol and CYP3A levels (r2=0.96). | 5beta-cholestane-3alpha | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 3 | From these results, it can be concluded that CYP3A4 is the predominant enzyme responsible for 25-hydroxylation of 5beta-cholestane-3alpha, 7alpha,12alpha-triol in human liver microsomes. | 5beta-cholestane-3alpha | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |