Title : Prevention of oxidant-induced cell death in Caco-2 colon carcinoma cells after inhibition of poly(ADP-ribose) polymerase and Ca2+ chelation: involvement of a common mechanism.

Pub. Date : 1999 Jan 1

PMID : 9920281






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The chelation of intracellular calcium by bis-(o-aminophenoxy)-ethane-N,N,N1,N1-tetraacidic acid/tetraacetoxymethyl) ester also prevented the dramatic loss of NAD+, demonstrating that Ca2+ is an activating factor in PARP-mediated cell killing. Calcium poly(ADP-ribose) polymerase 1 Homo sapiens