Title : Specific inhibition of iNOS decreases the intestinal mucosal peroxynitrite level and improves the barrier function after thermal injury.

Pub. Date : 1998 Dec

PMID : 9915669






3 Functional Relationships(s)
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1 This study was designed to investigate the effect of iNOS specific inhibitor S-methylisothiourea (SMT) on the postburn intestinal mucosal barrier function and the possible mechanism of SMT"s action. S-methylisothiopseudouronium nitric oxide synthase 2 Rattus norvegicus
2 This study was designed to investigate the effect of iNOS specific inhibitor S-methylisothiourea (SMT) on the postburn intestinal mucosal barrier function and the possible mechanism of SMT"s action. S-methylisothiopseudouronium nitric oxide synthase 2 Rattus norvegicus
3 After thermal injury in rats, administration of SMT for 2 days decreased the intestinal mucosal iNOS activity/ tNOS activity ratio and the BT incidence. S-methylisothiopseudouronium nitric oxide synthase 2 Rattus norvegicus