Pub. Date : 1999 Jan
PMID : 9914513
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In addition, ATP induces a conformational change in GroEL characterized by (a) the appearance of a reversible low temperature endotherm in the DSC profiles of the protein, and (b) an enhanced binding of the hydrophobic probe 8-anilino-naphthalene-1-sulfonate (ANS), which strictly depends on ATP hydrolysis. | 8-anilino-1-naphthalenesulfonic acid | heat shock protein family D (Hsp60) member 1 | Homo sapiens |
| 2 | In addition, ATP induces a conformational change in GroEL characterized by (a) the appearance of a reversible low temperature endotherm in the DSC profiles of the protein, and (b) an enhanced binding of the hydrophobic probe 8-anilino-naphthalene-1-sulfonate (ANS), which strictly depends on ATP hydrolysis. | 8-anilino-1-naphthalenesulfonic acid | heat shock protein family D (Hsp60) member 1 | Homo sapiens |
| 3 | The similar sensitivity to K+ of the temperature range where activation of the GroEL ATPase activity, the low temperature endotherm, and the increase of the ANS fluorescence are abserved strongly indicates the existence of a conformational state of GroEL during ATP hydrolysis, different from that generated on ADP or AMP-PNP binding. | 8-anilino-1-naphthalenesulfonic acid | heat shock protein family D (Hsp60) member 1 | Homo sapiens |