Protein Name heat shock protein family D (Hsp60) member 1
Organism Homo sapiens
Gene ID 3329
Gene Symbol

HSPD1

UniProt P10809 (CH60_HUMAN), A0A024R3X4 (A0A024R3X4_HUMAN)
Relationships Total Number of functionally related compound(s) : 453
Total Number of Articles : 676
Description

heat shock protein family D (Hsp60) member 1

Gene Summary

This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq, Jun 2010]

synonyms
  • 60 kDa heat shock protein, mitochondrial
  • 60 kDa chaperonin
  • P60 lymphocyte protein
Click to show/hide the synonyms
Properties