Title : Long-term maintenance of low concentrations of fructose for the study of hepatic glucose phosphorylation.

Pub. Date : 1999 Feb 1

PMID : 9895293






2 Functional Relationships(s)
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1 The stimulation of flux through glucokinase by low concentrations of fructose decreased the proportion of glucose phosphorylated, which was cycled between glucose and glucose 6-phosphate, and increased the proportion that was glycolysed. Glucose-6-Phosphate glucokinase Homo sapiens
2 The method described for maintaining the stimulation of glucose phosphorylation by isolated hepatocytes over prolonged incubation periods is especially suited to the further study of the control of glucokinase activity, in particular how the variation of flux through glucokinase affects the flux through all the pathways that utilize the product, glucose 6-phosphate. Glucose-6-Phosphate glucokinase Homo sapiens