Title : Endothelin-1 and blood pressure after inhibition of nitric oxide synthesis in human septic shock.

Pub. Date : 1999 Jan 19

PMID : 9892594






3 Functional Relationships(s)
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1 In this study, we tested whether ET-1 contributed to the vasopressor action of the NO synthase inhibitor NG-nitro-L-arginine methyl ester (L-NAME) in patients with severe septic shock. NG-Nitroarginine Methyl Ester endothelin 1 Homo sapiens
2 In this study, we tested whether ET-1 contributed to the vasopressor action of the NO synthase inhibitor NG-nitro-L-arginine methyl ester (L-NAME) in patients with severe septic shock. NG-Nitroarginine Methyl Ester endothelin 1 Homo sapiens
3 Although L-NAME does not increase ET-1 concentration in patients with septic shock, the vasopressor response induced by L-NAME depends on the plasma level of ET-1. NG-Nitroarginine Methyl Ester endothelin 1 Homo sapiens