Title : Activation of ERK by Ca2+ store depletion in rat liver epithelial cells.

Pub. Date : 1999 Jan

PMID : 9886938






2 Functional Relationships(s)
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1 In the first method, Ca2+ pool depletion by thapsigargin increased the activity of ERK, even when rise in cytosolic Ca2+ was blocked with the Ca2+ chelator BAPTA-AM. Thapsigargin carbonic anhydrase 2 Rattus norvegicus
2 The intracellular Ca2+-releasing agent thapsigargin increased Fyn activity, which was unaffected by BAPTA-AM pretreatment, suggesting that Fyn activity was unaffected by increased cytosolic free Ca2+. Thapsigargin carbonic anhydrase 2 Rattus norvegicus