Title : Endothelin and endothelin antagonists in hypertension.

Pub. Date : 1998 Dec

PMID : 9886874






1 Functional Relationships(s)
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1 Production of ET-1 is enhanced in several experimental models of hypertension in the rat, such as sodium-sensitive forms, e.g. deoxycorticosterone acetate (DOCA)-salt hypertensive, DOCA-salt-treated spontaneously hypertensive rats (SHR) and Dahl salt-sensitive rats, as well as other models such as stroke-prone SHR, angiotensin II-infused rats and fructose-fed rats, and possibly 1-K 1C Goldblatt hypertensive rats. Sodium endothelin 1 Rattus norvegicus