Pub. Date : 1999 Jan
PMID : 9884422
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To elucidate whether sulfonylureas directly influence renin secretion, the effect of tolbutamide, glibenclamide, or chlorpropamide on renin secretion was investigated by using the perfused kidney of the rat. | Chlorpropamide | renin | Rattus norvegicus |
| 2 | Renin activity significantly increased from a basal value of 11.7 +/- 3.6 to a peak value of 20.6 +/- 5.5 ng/Ang I/ml/h with tolbutamide, from 14.4 +/- 4.6 to 32.7 +/- 6.5 ng/Ang I/ml/h with glibenclamide, and from 15.0 +/- 4.9 to 30.4 +/- 6.1 ng/Ang I/ml/h with chlorpropamide. | Chlorpropamide | renin | Rattus norvegicus |