Pub. Date : 1999 Jan 15
PMID : 9880490
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The results indicate that HCO3- competes with other anions for the anion-binding site of SOD1 (Arg141) but does not bind directly to the copper. | Bicarbonates | superoxide dismutase 1 | Homo sapiens |
2 | Thus, SOD1 acquires peroxidase activity at physiological pH only in the presence of HCO3- or structurally similar anions. | Bicarbonates | superoxide dismutase 1 | Homo sapiens |
3 | Alterations in pH that shift the HCO3-/CO2 equilibrium as occur in disease processes such as ischemia, sepsis, or shock would modulate the peroxidase function of SOD1. | Bicarbonates | superoxide dismutase 1 | Homo sapiens |