Title : Synthesis of 5-substituted quinazolinone derivatives and their inhibitory activity in vitro.

Pub. Date : 1998 Dec 1

PMID : 9873719






1 Functional Relationships(s)
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1 Quinazolinone derivatives I and their methyl esters were synthesized and evaluated as nonclassical lipophilic inhibitors of thymidylate synthase. methyl esters thymidylate synthetase Homo sapiens