Title : Altered localization of E-cadherin and alpha-catenin in rat esophageal tumors.

Pub. Date : 1999 Jan

PMID : 9863006






2 Functional Relationships(s)
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1 Immunohistochemical analysis of NMBA-induced esophageal neoplasms in rats revealed E-cadherin and alpha-catenin to be abnormally expressed in poorly differentiated tumors when compared to well differentiated tumors. nitrosobenzylmethylamine cadherin 1 Rattus norvegicus
2 These results suggest that the microenvironment may have an important role in regulating the expression of these adhesion molecules in rat esophageal epithelial cells, and that alteration in the cellular localization of E-cadherin and alpha-catenin may be indicative of tumor progression in NMBA-induced rat esophageal cancer. nitrosobenzylmethylamine cadherin 1 Rattus norvegicus