| Protein Name | cadherin 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 83502 |
| Gene Symbol | Cdh1 |
| UniProt | Q9R0T4 (CADH1_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
207
Total Number of Articles : 230 |
Description |
cadherin 1 |
| Gene Summary |
Enables beta-catenin binding activity and protein tyrosine kinase binding activity. Involved in several processes, including nervous system development; regulation of protein catabolic process at postsynapse, modulating synaptic transmission; and response to Gram-positive bacterium. Is active in glutamatergic synapse and postsynapse. Used to study hepatocellular carcinoma and lung adenocarcinoma. Biomarker of pulmonary fibrosis and urinary bladder cancer. Human ortholog(s) of this gene implicated in several diseases, including blepharocheilodontic syndrome 1; breast cancer (multiple); carcinoma (multiple); cervix uteri carcinoma in situ; and reproductive organ cancer (multiple). Orthologous to human CDH1 (cadherin 1). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |