Title : Protein kinase Cdelta-dependent induction of manganese superoxide dismutase gene expression by microtubule-active anticancer drugs.

Pub. Date : 1998 Dec 18

PMID : 9852137






4 Functional Relationships(s)
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1 Down-regulation of PKC by prolonged treatment with phorbol 12-myristate 13-acetate (PMA) also inhibited induction of MnSOD by anticancer drugs, indicating an important role of PKC in MnSOD signaling by these agents. Tetradecanoylphorbol Acetate superoxide dismutase 2 Homo sapiens
2 Down-regulation of PKC by prolonged treatment with phorbol 12-myristate 13-acetate (PMA) also inhibited induction of MnSOD by anticancer drugs, indicating an important role of PKC in MnSOD signaling by these agents. Tetradecanoylphorbol Acetate superoxide dismutase 2 Homo sapiens
3 Down-regulation of PKC by prolonged treatment with phorbol 12-myristate 13-acetate (PMA) also inhibited induction of MnSOD by anticancer drugs, indicating an important role of PKC in MnSOD signaling by these agents. Tetradecanoylphorbol Acetate superoxide dismutase 2 Homo sapiens
4 Down-regulation of PKC by prolonged treatment with phorbol 12-myristate 13-acetate (PMA) also inhibited induction of MnSOD by anticancer drugs, indicating an important role of PKC in MnSOD signaling by these agents. Tetradecanoylphorbol Acetate superoxide dismutase 2 Homo sapiens