Title : Effects of endogenous superoxide anion and nitric oxide on cholinergic constriction of normal and hyperreactive guinea pig airways.

Pub. Date : 1998 Dec

PMID : 9847268






1 Functional Relationships(s)
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1 In the presence of the NO synthase (NOS) inhibitor N omega-nitro-L-arginine methyl ester (L-NAME; 100 microM), tracheae obtained from unchallenged guinea pigs showed a 1.7-fold increase in the maximal response to intraluminally applied methacholine (p < 0.05). Methacholine Chloride nitric oxide synthase, inducible Cavia porcellus