Pub. Date : 1998
PMID : 9820121
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effects of suramin on human platelet aggregation and Ca2+ mobilization induced by thrombin and other agonists. | Suramin | coagulation factor II, thrombin | Homo sapiens |
| 2 | Our results show that suramin completely inhibited aggregation by thrombin, platelet activating factor (PAF), alkyllysophosphatidic acid (ALPA), or arachidonic acid in a concentration-dependent manner. | Suramin | coagulation factor II, thrombin | Homo sapiens |
| 3 | The IC50 values of suramin for inhibition of aggregation by PAF, arachidonic acid, and thrombin were 76.7, 239, and 1.49 microg/ml, respectively. | Suramin | coagulation factor II, thrombin | Homo sapiens |
| 4 | Ca2+ mobilization induced by thrombin was inhibited by suramin with an approximate IC50 value of 20 microg/ml. | Suramin | coagulation factor II, thrombin | Homo sapiens |