Pub. Date : 1997 Mar
PMID : 9815696
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mitotane, at a concentration achieved in this patient"s plasma, completely reversed the Pgp-related resistance both in the Pgp-overexpressing KB8-5 cell line and in the patient"s tumor cells. | Mitotane | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | Mitotane, at a concentration achieved in this patient"s plasma, completely reversed the Pgp-related resistance both in the Pgp-overexpressing KB8-5 cell line and in the patient"s tumor cells. | Mitotane | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | On the basis of these in vitro results, the patient was treated with a combination of multidrug resistance drugs (doxorubicin, vincristine, and etoposide) plus mitotane as a Pgp modulator. | Mitotane | ATP binding cassette subfamily B member 1 | Homo sapiens |