Pub. Date : 1998 Nov 15
PMID : 9806908
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cholesterol regulates oxysterol binding protein (OSBP) phosphorylation and Golgi localization in Chinese hamster ovary cells: correlation with stimulation of sphingomyelin synthesis by 25-hydroxycholesterol. | Cholesterol | LOW QUALITY PROTEIN: oxysterol-binding protein 1 | Cricetulus griseus |
| 2 | Cholesterol regulates oxysterol binding protein (OSBP) phosphorylation and Golgi localization in Chinese hamster ovary cells: correlation with stimulation of sphingomyelin synthesis by 25-hydroxycholesterol. | Cholesterol | LOW QUALITY PROTEIN: oxysterol-binding protein 1 | Cricetulus griseus |
| 3 | The potential role of oxysterols and oxysterol binding protein (OSBP) in mediating the coregulation of cholesterol and SM was examined using Chinese hamster ovary (CHO) and cholesterol auxotrophic, sterol regulatory defective (SRD) 6 cells. | Cholesterol | LOW QUALITY PROTEIN: oxysterol-binding protein 1 | Cricetulus griseus |
| 4 | The potential role of oxysterols and oxysterol binding protein (OSBP) in mediating the coregulation of cholesterol and SM was examined using Chinese hamster ovary (CHO) and cholesterol auxotrophic, sterol regulatory defective (SRD) 6 cells. | Cholesterol | LOW QUALITY PROTEIN: oxysterol-binding protein 1 | Cricetulus griseus |
| 5 | The potential role of oxysterols and oxysterol binding protein (OSBP) in mediating the coregulation of cholesterol and SM was examined using Chinese hamster ovary (CHO) and cholesterol auxotrophic, sterol regulatory defective (SRD) 6 cells. | Cholesterol | LOW QUALITY PROTEIN: oxysterol-binding protein 1 | Cricetulus griseus |
| 6 | Unlike CHO 7 cells, where OSBP was observed in small vesicles and the cytoplasm, OSBP in cholesterol-starved SRD 6 cells was constitutively localized in the Golgi apparatus. | Cholesterol | LOW QUALITY PROTEIN: oxysterol-binding protein 1 | Cricetulus griseus |
| 7 | Low-density lipoprotein (LDL) supplementation of CHO-K1 cells caused the redistribution of OSBP to the cytoplasm and small vesicles, and this effect was blocked by pharmacological agents ?3-beta-[2-(diethylamino)ethoxy]androst-5-en-17-one and progesterone?, which inhibited LDL cholesterol efflux from lysosomes. | Cholesterol | LOW QUALITY PROTEIN: oxysterol-binding protein 1 | Cricetulus griseus |
| 8 | The results showed that localization of OSBP between the Golgi apparatus and a cytoplasmic/vesicular compartment was responsive to changes in cholesterol content and trafficking. | Cholesterol | LOW QUALITY PROTEIN: oxysterol-binding protein 1 | Cricetulus griseus |
| 9 | In cholesterol depleted SRD 6 cells, this was accompanied by dephosphorylation of OSBP and attenuation of 25-hydroxycholesterol activation of SM synthesis. | Cholesterol | LOW QUALITY PROTEIN: oxysterol-binding protein 1 | Cricetulus griseus |