Title : Involvement of a local fenton reaction in the reciprocal modulation by O2 of the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene and the insulin-dependent activation of the glucokinase gene in rat hepatocytes.

Pub. Date : 1998 Oct 15

PMID : 9761743






4 Functional Relationships(s)
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1 H2O2 mimicked the action of periportal pO2 in the modulation by O2 of the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase (PCK) gene and the insulin-dependent activation of the glucokinase (GK) gene. PO-2 phosphoenolpyruvate carboxykinase 1 Rattus norvegicus
2 H2O2 mimicked the action of periportal pO2 in the modulation by O2 of the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase (PCK) gene and the insulin-dependent activation of the glucokinase (GK) gene. PO-2 phosphoenolpyruvate carboxykinase 1 Rattus norvegicus
3 PCK mRNA was induced by glucagon maximally under conditions of periportal pO2 and half-maximally under venous pO2. PO-2 phosphoenolpyruvate carboxykinase 1 Rattus norvegicus
4 PCK mRNA was induced by glucagon maximally under conditions of periportal pO2 and half-maximally under venous pO2. PO-2 phosphoenolpyruvate carboxykinase 1 Rattus norvegicus